Calithera Biosciences (NASDAQ:CALA) & Amneal Pharmaceuticals (NYSE:AMRX) Head-To-Head Survey

Calithera Biosciences (NASDAQ:CALAGet Rating) and Amneal Pharmaceuticals (NYSE:AMRXGet Rating) are both small-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, earnings, valuation, risk, analyst recommendations, profitability and institutional ownership.


This table compares Calithera Biosciences and Amneal Pharmaceuticals’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Calithera Biosciences N/A -98.80% -70.71%
Amneal Pharmaceuticals 0.68% 61.08% 5.68%

Analyst Ratings

This is a summary of current ratings and price targets for Calithera Biosciences and Amneal Pharmaceuticals, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Calithera Biosciences 0 2 2 0 2.50
Amneal Pharmaceuticals 0 0 0 0 N/A

Calithera Biosciences currently has a consensus target price of $3.33, indicating a potential upside of 1,194.50%. Given Calithera Biosciences’ higher probable upside, equities analysts plainly believe Calithera Biosciences is more favorable than Amneal Pharmaceuticals.

Earnings and Valuation

This table compares Calithera Biosciences and Amneal Pharmaceuticals’ gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Calithera Biosciences $9.75 million 1.98 -$115.09 million ($1.54) -0.17
Amneal Pharmaceuticals $1.99 billion 0.59 $91.06 million $0.09 43.11

Amneal Pharmaceuticals has higher revenue and earnings than Calithera Biosciences. Calithera Biosciences is trading at a lower price-to-earnings ratio than Amneal Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

Volatility and Risk

Calithera Biosciences has a beta of 1.48, indicating that its share price is 48% more volatile than the S&P 500. Comparatively, Amneal Pharmaceuticals has a beta of 1.24, indicating that its share price is 24% more volatile than the S&P 500.

Institutional & Insider Ownership

54.8% of Calithera Biosciences shares are held by institutional investors. Comparatively, 38.5% of Amneal Pharmaceuticals shares are held by institutional investors. 11.9% of Calithera Biosciences shares are held by insiders. Comparatively, 26.6% of Amneal Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.


Amneal Pharmaceuticals beats Calithera Biosciences on 8 of the 13 factors compared between the two stocks.

About Calithera Biosciences (Get Rating)

Calithera Biosciences, Inc., a clinical-stage bio-pharmaceutical company, focuses on the discovery and development of small molecule compounds for tumor metabolism and tumor immunology targets for the treatment of cancer in the United States. The company offers INCB001158, an orally bioavailable arginase inhibitor of arginase that is in Phase 1/2 clinical trial for the treatment of hematology and oncology. It is developing CB-280, an oral arginase inhibitor that has completed Phase 1b clinical trial for the treatment of cystic fibrosis and chronic airway infection; and ATG-037, an orally-bioavailable small molecule inhibitor of CD73, as well as CB-668, an orally administered inhibitor of the enzyme IL4I1. The company has a license agreement with Mars, Inc. to develop and commercialize Symbioscience's portfolio of arginase inhibitors for use in human healthcare. It also has clinical trial collaboration with Pfizer to evaluate Pfizer's PARP inhibitor talazoparib and CDK4/6 inhibitor palbociclib, each in combination with telaglenasta. In addition, the company has a collaboration and license agreement with Incyte Corporation for the research, development, and commercialization of INCB001158, a small molecule arginase inhibitor for the treatment of hematology and oncology; and a license agreement with Antengene Corporation Ltd. for the development and commercialization of CB-708. Calithera Biosciences, Inc. was incorporated in 2010 and is headquartered in South San Francisco, California.

About Amneal Pharmaceuticals (Get Rating)

Amneal Pharmaceuticals, Inc., together with its subsidiaries, develops, licenses, manufactures, markets, and distributes generic and specialty pharmaceutical products for various dosage forms and therapeutic areas. The company operates through three segments: Generics, Specialty, and AvKARE. The Generics segment develops, manufactures, and commercializes complex oral solids, injectables, ophthalmics, liquids, topicals, softgels, inhalation products, and transdermals across a range of therapeutic categories. The Specialty segment is involved in the development, promotion, distribution, and sale of branded pharmaceutical products with focus on central nervous system disorders, endocrinology, parasitic infections, and other therapeutic areas. It also offers Emverm, a chewable tablet for the treatment of pinworm, whipworm, common roundworm, common hookworm, and American hookworm in single or mixed infections; Rytary to treat Parkinson's disease; and Unithroid for the treatment of hypothyroidism. The AvKARE segment provides pharmaceuticals, medical and surgical products, and services primarily to governmental agencies, the Department of Defense, and the Department of Veterans Affairs. It is also involved in the wholesale distribution of bottle and unit dose pharmaceuticals under the AvKARE and AvPAK names, as well as medical and surgical products; and packaging and wholesale distribution of pharmaceuticals and vitamins to its retail and institutional customers. The company sells its products through wholesalers, distributors, hospitals, chain pharmacies, and individual pharmacies. It operates in the United States, India, Ireland, and internationally. The company was formerly known as Atlas Holdings, Inc. and changed its name to Amneal Pharmaceuticals, Inc. in 2018. Amneal Pharmaceuticals, Inc. was founded in 2002 and is headquartered in Bridgewater, New Jersey.

Receive News & Ratings for Calithera Biosciences Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Calithera Biosciences and related companies with's FREE daily email newsletter.