Head-To-Head Contrast: Aileron Therapeutics (NASDAQ:ALRN) & Oculis (NASDAQ:OCS)

Aileron Therapeutics (NASDAQ:ALRN) and Oculis (NASDAQ:OCS) are both small-cap medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their profitability, analyst recommendations, earnings, institutional ownership, dividends, valuation and risk.

Valuation and Earnings

This table compares Aileron Therapeutics and Oculis’ revenue, earnings per share (EPS) and valuation.

	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Aileron Therapeutics	N/A	N/A	-$27.33 million	N/A	N/A
Oculis	$960,000.00	371.84	-$40.55 million	N/A	N/A

Aileron Therapeutics has higher earnings, but lower revenue than Oculis.

Institutional and Insider Ownership

22.5% of Aileron Therapeutics shares are owned by institutional investors. Comparatively, 14.3% of Oculis shares are owned by institutional investors. 3.5% of Aileron Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Profitability

This table compares Aileron Therapeutics and Oculis’ net margins, return on equity and return on assets.

	Net Margins	Return on Equity	Return on Assets
Aileron Therapeutics	N/A	-83.80%	-72.25%
Oculis	N/A	N/A	N/A

Analyst Ratings

This is a summary of recent ratings and price targets for Aileron Therapeutics and Oculis, as provided by MarketBeat.com.

	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Aileron Therapeutics	0	0	0	0	N/A
Oculis	0	0	8	0	3.00

Oculis has a consensus target price of $33.67, suggesting a potential upside of 243.19%. Given Oculis’ higher possible upside, analysts plainly believe Oculis is more favorable than Aileron Therapeutics.

Summary

Oculis beats Aileron Therapeutics on 5 of the 8 factors compared between the two stocks.

About Aileron Therapeutics

Aileron Therapeutics, Inc. operates as a clinical stage chemoprotection oncology company in the United States. The company is developing ALRN-6924, which is in Phase 1 trial for solid tumor and lymphoma; Phase 2a clinical trial to treat peripheral T-cell lymphoma; Phase I clinical trial for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS); Phase 1b trial to test the combination of ALRN-6924 and cytarabine, or Ara-C, in patients with MDS; and a Phase 2a combination trial of ALRN-6924 and palbociclib in patients with tumors harboring MDM2 amplifications co-amplifications, as well as for patients with p53-mutated small cell lung cancer that has completed Phase 1b clinical trial. The company was formerly known as Renegade Therapeutics, Inc. and changed its name to Aileron Therapeutics, Inc. in February 2007. Aileron Therapeutics, Inc. was incorporated in 2001 and is headquartered in Boston, Massachusetts.

About Oculis

Oculis Holding AG, a clinical-stage biopharmaceutical company, develops novel topical treatments for ophthalmic diseases for both back- and front-of-the-eye. The company's lead candidate is OCS-01, a topical dexamethasone formulation, which is in Phase 3 clinical trials for the treatment of diabetic macular edema; OCS-02, a topical biologic candidate that is in Phase 2b clinical trials for the treatment for keratoconjunctivitis sicca, or dry eye disease; and OCS-05, a novel neuroprotective agent for acute optic neuritis and other neuro-ophtha disorders, such as glaucoma, diabetic retinopathy, geographic atrophy, and neurotrophic keratitis. The company is based in Zug, Switzerland.