Reviewing Barinthus Biotherapeutics (NASDAQ:BRNS) and Astellas Pharma (OTCMKTS:ALPMY)

Barinthus Biotherapeutics (NASDAQ:BRNSGet Free Report) and Astellas Pharma (OTCMKTS:ALPMYGet Free Report) are both medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, dividends, valuation, earnings, analyst recommendations, risk and institutional ownership.

Profitability

This table compares Barinthus Biotherapeutics and Astellas Pharma’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Barinthus Biotherapeutics N/A -33.63% -28.88%
Astellas Pharma 3.26% 10.33% 4.62%

Analyst Recommendations

This is a breakdown of current ratings and recommmendations for Barinthus Biotherapeutics and Astellas Pharma, as provided by MarketBeat.com.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Barinthus Biotherapeutics 0 0 4 0 3.00
Astellas Pharma 0 0 0 0 0.00

Barinthus Biotherapeutics presently has a consensus target price of $5.83, indicating a potential upside of 332.10%. Given Barinthus Biotherapeutics’ stronger consensus rating and higher possible upside, analysts plainly believe Barinthus Biotherapeutics is more favorable than Astellas Pharma.

Institutional & Insider Ownership

25.2% of Barinthus Biotherapeutics shares are owned by institutional investors. 8.0% of Barinthus Biotherapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Volatility & Risk

Barinthus Biotherapeutics has a beta of -0.59, suggesting that its share price is 159% less volatile than the S&P 500. Comparatively, Astellas Pharma has a beta of 0.36, suggesting that its share price is 64% less volatile than the S&P 500.

Earnings and Valuation

This table compares Barinthus Biotherapeutics and Astellas Pharma”s gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Barinthus Biotherapeutics $800,000.00 66.52 -$73.35 million ($1.49) -0.91
Astellas Pharma $11.11 billion 1.82 $113.00 million $0.21 53.19

Astellas Pharma has higher revenue and earnings than Barinthus Biotherapeutics. Barinthus Biotherapeutics is trading at a lower price-to-earnings ratio than Astellas Pharma, indicating that it is currently the more affordable of the two stocks.

Summary

Astellas Pharma beats Barinthus Biotherapeutics on 8 of the 14 factors compared between the two stocks.

About Barinthus Biotherapeutics

(Get Free Report)

Barinthus Biotherapeutics plc, a clinical-stage biopharmaceutical company, engages in development of novel T cell immunotherapeutic candidates designed to guide the immune system to overcome chronic infectious diseases, autoimmunity, and cancer. The company's development pipeline includes VTP-300, an immunotherapeutic candidate under phase 2 studies as a potential component of a functional cure for chronic hepatitis B virus (HBV) infection; VTP-200, a non-surgical product candidate under phase 2 studies for treating persistent high-risk human papillomavirus (HPV) infection; VTP-1000, an autoimmune preclinical candidate designed to treat patients with celiac disease; VTP-1100 product candidate to target HPV16+ cancers; and VTP-850/850, a second-generation immunotherapeutic candidate under phase 2 studies to treat recurrent prostate cancer. It is also involved in the development of partnered candidates, such as AB-729-202, which is under phase 2a studies for the treatment of patients with chronic HBV infection; VTP-600, an immunotherapy candidate under phase 1 studies as a potential treatment for NSCLC in combination with standard of care treatment, chemotherapy, and pembrolizumab; VTP-500, a prophylactic vaccine product candidate under phase 1 studies to prevent infection and subsequent disease caused by the MERS coronavirus; and VTP-400, a prophylactic vaccine candidate under phase 1 studies to prevent shingles in adults aged 50 years and older. In addition, the company offers Vaxzevria (formerly VTP-900 and AZD1222), a prophylactic vaccine for the prevention of COVID-19 Infection. Further, it has license, research and development, and collaboration agreements with OUI, NIH, IMC, CanSino, CRUK; VOLT; and Arbutus. The company was formerly known as Vaccitech plc and changed its name to Barinthus Biotherapeutics plc in November 2023. Barinthus Biotherapeutics plc was founded in 2016 and is headquartered in Didcot, the United Kingdom.

About Astellas Pharma

(Get Free Report)

Astellas Pharma Inc. manufactures, markets, and imports and exports pharmaceuticals in Japan and internationally. The company provides XTANDI, a treatment for prostate cancer; XOSPATA, a treatment for patients who have relapsed or refractory acute myeloid leukemia with a FLT3 mutation; and PADCEV, a treatment for patients with metastatic urothelial cancer. It also offers Evrenzo, a treatment for anemia associated with chronic kidney disease; Betanis/Myrabetriq/BETMIGA, a treatment for overactive bladder; and Prograf and Advagraf/Graceptor/ASTAGRAF XL immunosuppressants. Th company has a research collaboration with Vivtex Corporation to evaluate Vivtex’s GI-ORIS screening and formulation platform technology to support the development of novel and oral versions of a therapeutic candidate provided by Astellas; and a partnership agreement with Roche Diabetes Care Japan Co., Ltd. to develop and commercialize integrated diabetes self-management solution. The company was founded in 1923 and is headquartered in Tokyo, Japan.

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