Contrasting AstraZeneca (NASDAQ:AZN) and Onconetix (NASDAQ:ONCO)

Onconetix (NASDAQ:ONCOGet Free Report) and AstraZeneca (NASDAQ:AZNGet Free Report) are both medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their institutional ownership, valuation, earnings, risk, dividends, analyst recommendations and profitability.

Insider & Institutional Ownership

23.9% of Onconetix shares are owned by institutional investors. Comparatively, 20.4% of AstraZeneca shares are owned by institutional investors. 1.0% of Onconetix shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Analyst Ratings

This is a summary of recent recommendations for Onconetix and AstraZeneca, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Onconetix 1 0 0 0 1.00
AstraZeneca 1 0 10 0 2.82

AstraZeneca has a consensus target price of $95.75, suggesting a potential downside of 48.98%. Given AstraZeneca’s stronger consensus rating and higher probable upside, analysts clearly believe AstraZeneca is more favorable than Onconetix.

Profitability

This table compares Onconetix and AstraZeneca’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Onconetix -4,011.43% -632.63% -160.97%
AstraZeneca 16.17% 32.89% 13.00%

Earnings and Valuation

This table compares Onconetix and AstraZeneca”s gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Onconetix $2.52 million 0.83 -$58.69 million $10.89 0.12
AstraZeneca $58.13 billion 10.02 $7.04 billion $3.01 62.35

AstraZeneca has higher revenue and earnings than Onconetix. Onconetix is trading at a lower price-to-earnings ratio than AstraZeneca, indicating that it is currently the more affordable of the two stocks.

Volatility and Risk

Onconetix has a beta of 3.45, indicating that its share price is 245% more volatile than the S&P 500. Comparatively, AstraZeneca has a beta of 0.34, indicating that its share price is 66% less volatile than the S&P 500.

Summary

AstraZeneca beats Onconetix on 10 of the 14 factors compared between the two stocks.

About Onconetix

(Get Free Report)

Onconetix, Inc., a biotechnology company, focuses on the research, development, and commercialization of solutions for men's health and oncology. It offers Entadfi, an FDA-approved, once daily pill that combines finasteride and tadalafil for the treatment of benign prostatic hyperplasia; and Proclarix, an in vitro protein-based blood diagnostic test for prostate cancer. The company was formerly known as Blue Water Biotech, Inc. and changed its name to Onconetix, Inc. in December 2023. Onconetix, Inc. was incorporated in 2018 and is headquartered in Cincinnati, Ohio.

About AstraZeneca

(Get Free Report)

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company’s marketed products include Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Farxiga, Brilinta, Lokelma, Roxadustat, Andexxa, Crestor, Seloken, Onglyza, Bydureon, Fasenra, Breztri, Symbicort, Saphnelo, Tezspire, Pulmicort, Bevespi, and Daliresp for cardiovascular, renal, metabolism, and oncology. Its marketed products also comprise Vaxzevria, Beyfortus, Synagis, FluMist, Soliris, Ultomiris, Strensiq, Koselugo, and Kanuma for covid-19 and rare disease. The company serves primary care and specialty care physicians through distributors and local representative offices in the United Kingdom, rest of Europe, the Americas, Asia, Africa, and Australasia. It has a collaboration agreement with Neurimmune AG to develop and commercialize NI006; BenevolentAI for drug discovery for systemic lupus erythematosus; and Absci Corporation for AI-driven drug discovery against an oncology target. The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom.

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