Immuneering (NASDAQ:IMRX – Get Free Report) and Axsome Therapeutics (NASDAQ:AXSM – Get Free Report) are both medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their dividends, earnings, valuation, institutional ownership, profitability, risk and analyst recommendations.
Institutional & Insider Ownership
67.7% of Immuneering shares are owned by institutional investors. Comparatively, 81.5% of Axsome Therapeutics shares are owned by institutional investors. 22.9% of Immuneering shares are owned by insiders. Comparatively, 22.3% of Axsome Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.
Valuation & Earnings
This table compares Immuneering and Axsome Therapeutics”s revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Immuneering | N/A | N/A | -$61.04 million | ($1.78) | -2.66 |
| Axsome Therapeutics | $385.69 million | 24.25 | -$287.22 million | ($4.67) | -39.73 |
Immuneering has higher earnings, but lower revenue than Axsome Therapeutics. Axsome Therapeutics is trading at a lower price-to-earnings ratio than Immuneering, indicating that it is currently the more affordable of the two stocks.
Analyst Recommendations
This is a summary of recent recommendations and price targets for Immuneering and Axsome Therapeutics, as reported by MarketBeat.com.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Immuneering | 1 | 0 | 5 | 1 | 2.86 |
| Axsome Therapeutics | 2 | 0 | 19 | 0 | 2.81 |
Immuneering currently has a consensus price target of $16.50, indicating a potential upside of 248.10%. Axsome Therapeutics has a consensus price target of $208.72, indicating a potential upside of 12.49%. Given Immuneering’s stronger consensus rating and higher possible upside, equities research analysts plainly believe Immuneering is more favorable than Axsome Therapeutics.
Risk and Volatility
Immuneering has a beta of 0.46, meaning that its share price is 54% less volatile than the S&P 500. Comparatively, Axsome Therapeutics has a beta of 0.4, meaning that its share price is 60% less volatile than the S&P 500.
Profitability
This table compares Immuneering and Axsome Therapeutics’ net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Immuneering | N/A | -73.49% | -65.01% |
| Axsome Therapeutics | -40.90% | -277.31% | -28.81% |
Summary
Immuneering beats Axsome Therapeutics on 10 of the 14 factors compared between the two stocks.
About Immuneering
Immuneering Corporation, a clinical-stage oncology company, engages in the development of medicines for broad populations of cancer patients. Its lead product candidates include IMM-1-104, a dual-MEK inhibitor currently under Phase 1/2a clinical trial to treat patients with cancer, including pancreatic, melanoma, colorectal, and non-small cell lung cancer caused by mutations of RAS and/or RAF; and IMM-6-415 is in Investigational New Drug application to treat solid tumors. Immuneering Corporation was incorporated in 2008 and is based in Cambridge, Massachusetts.
About Axsome Therapeutics
Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company’s commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist with multimodal activity indicated for the treatment of major depressive disorder; and Sunosi (solriamfetol), a medication indicated to the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea. It is also developing AXS-05, which is in Phase III clinical trial to treat Alzheimer’s disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation; AXS-07, an investigational medicine that has completed Phase III trials for the acute treatment of migraine; AXS-12, an investigational medicine, which is in Phase III trial to treat narcolepsy; AXS-14, a selective and potent norepinephrine reuptake inhibitor that has completed Phase III trial for the treatment of fibromyalgia and other conditions; and solriamfetol, a dual-acting dopamine and norepinephrine reuptake inhibitor, which has completed a Phase 2 trial for treating attention-deficit/hyperactivity disorder, and is in phase 2 major depressive, binge eating, and shift work disorder. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.
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