Semler Scientific (NASDAQ:SMLR – Get Free Report) and ENDRA Life Sciences (NASDAQ:NDRA – Get Free Report) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their valuation, profitability, risk, institutional ownership, analyst recommendations, earnings and dividends.
Valuation & Earnings
This table compares Semler Scientific and ENDRA Life Sciences”s top-line revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Semler Scientific | $56.29 million | 8.16 | $40.90 million | $2.43 | 12.77 |
| ENDRA Life Sciences | N/A | N/A | -$11.51 million | ($33.89) | -0.17 |
Risk and Volatility
Semler Scientific has a beta of 1.41, suggesting that its share price is 41% more volatile than the S&P 500. Comparatively, ENDRA Life Sciences has a beta of -0.09, suggesting that its share price is 109% less volatile than the S&P 500.
Analyst Recommendations
This is a summary of current ratings and price targets for Semler Scientific and ENDRA Life Sciences, as provided by MarketBeat.com.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Semler Scientific | 0 | 0 | 4 | 0 | 3.00 |
| ENDRA Life Sciences | 0 | 0 | 1 | 0 | 3.00 |
Semler Scientific presently has a consensus price target of $74.25, indicating a potential upside of 139.28%. ENDRA Life Sciences has a consensus price target of $50.00, indicating a potential upside of 789.68%. Given ENDRA Life Sciences’ higher probable upside, analysts plainly believe ENDRA Life Sciences is more favorable than Semler Scientific.
Institutional & Insider Ownership
49.4% of Semler Scientific shares are held by institutional investors. Comparatively, 1.2% of ENDRA Life Sciences shares are held by institutional investors. 16.4% of Semler Scientific shares are held by company insiders. Comparatively, 0.0% of ENDRA Life Sciences shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.
Profitability
This table compares Semler Scientific and ENDRA Life Sciences’ net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Semler Scientific | 86.20% | 43.84% | 32.88% |
| ENDRA Life Sciences | N/A | -194.14% | -127.89% |
Summary
Semler Scientific beats ENDRA Life Sciences on 11 of the 12 factors compared between the two stocks.
About Semler Scientific
Semler Scientific, Inc. provides technology solutions to enhance the clinical effectiveness and efficiency of healthcare providers in the United States. The company’s products include QuantaFlo, a four-minute in-office blood flow test that enables healthcare providers to use blood flow measurements as part of their examinations of a patient’s vascular condition. It also offers Insulin Insights, a software program that is used by a healthcare provider to optimize outpatient insulin dosing. The company’s products serve cardiologists, internists, nephrologists, endocrinologists, podiatrists, family practitioners, healthcare insurance plans, integrated delivery networks, independent physician groups, and companies contracting with the healthcare industry, such as risk assessment groups and retailers. It offers its products through sales representatives and distributors. The company was incorporated in 2007 and is headquartered in Santa Clara, California.
About ENDRA Life Sciences
ENDRA Life Sciences Inc. develops technologies to improve the capabilities of clinical diagnostic ultrasound. The company is developing thermo-acoustic enhanced ultrasound technology that uses radio frequency pulses to generate ultrasonic waves in tissue to create high-contrast images for use in the treatment of nonalcoholic fatty liver disease, as well as in tissue composition, temperature monitoring, vascular imaging, and tissue perfusion. It has a collaborative research agreement with General Electric Company. ENDRA Life Sciences Inc. was incorporated in 2007 and is based in Ann Arbor, Michigan.
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